Vinylpyrrolidone Vinyl Acetate Copolymers

2005 vinylpyrrolidone vinyl acetate copolymer copovidone.

Vinylpyrrolidone vinyl acetate copolymers.

Polymers in the four ranges of vinylpyrrolidone content 30 50 60 and 70 percent are produced in ethanol or isopropanol. Copovidone vinylpyrrolidone vinyl acetate copolymer a more plastic and less hygroscopic copolymer is also having a high binding capacity and hence used as a dry binder in direct compression technique. Poly 1 vinylpyrrolidone co vinyl acetate 64 or pvp va64 contains 1 vinylpyrrolidone and vinyl acetate in the ratio of 6 4. Copovidone is also used as a solubilizing agent granulating agent retardant and film former.

Linear random copolymers of vinyl pyrrolidone vp and vinyl acetate va family includes both hydrophobic and hydrophilic thermoplastic oxygen permeable polymers solubility varies with the proportion of vinyl acetate insoluble in ethers and aliphatic hydrocarbons soluble in water if vp content is greater than 50. Water soluble copolymers with vinylpyrrolidone are used as color transfer inhibitors in detergent preparations with vinyl acetate as a coating of lithographic printing plates with acrylic acid esters or methacrylic acid esters or 2 hydroxyethyl methacrylate as adhesion promoters in paints or with acrylonitrile as precursors for carbon fibers. Poly 1 vinylpyrrolidone co vinyl acetate average mw 50 000 gpc vs. Pvp va copolymers are available as white powders or clear solutions in ethanol isopropanol and water.

Therefore combining vinylpyrrolidone with water insoluble vinyl acetate results in a copolymer that is still appreciably soluble in a variety of solvents but slightly more hydrophobic. Cite this chapter as. Acetic acid vinyl ester polymer with 1 vinyl 2 pyrrolidinone. Vp va copolymers are with different rations of vinylpyrrolidone to vinyl acetate and available as white powder or clear transparent solutions in water ethanol and isopropanol it s forms hard glossy flexible water removable oxygen permeable films which adhere to glass plastics and metals these pro.

Polyvinylpyrrolidone excipients for pharmaceuticals. Copolymer is widely used in the production of the solid dispersion due to its good effect in the stabilization of solid dispersions.